Nlgn4l antibody (AA 782-945)

Catalog No. ABIN6657914

Supplier Product No.: 200-301-w81

Product Details anti-Nlgn4l Antibody

Target: Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))

Binding Specificity: AA 782-945

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Nlgn4l antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Fluorescence Microscopy (FM)

Supplier Product No.: 200-301-w81

Supplier: Rockland

Purpose: Neuroligin 4 Antibody

Cross-Reactivity (Details): BLAST analysis suggests that it is ~45 % identical to Neuroligin -1, -2, and -3.

Purification: Anti-Neuroligin 4 Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: Anti-Neuroligin 4 Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 782-945 of mouse Neuroligin 4.

Clone: S98-7

Isotype: IgG1

Application Details

Application Notes:

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: 1:100

IF_Microscopy_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Comment:

Anti-Neuroligin 4 Antibody is tested for Western Blots, Immunofluorescence (Primary) and Immunocytochemistry. Expect a band approximately ~125-130kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for Nlgn4l

Target: Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))

Alternative Name: Nlgn4l (NLGN4L Products)

Background:

Synonyms: ASPGX2 antibody, AUTSX2 antibody, HLNX antibody, HNLX antibody, KIAA1260 antibody, MGC22376 antibody, NLGN antibody, NLGN4 antibody, NLGN4X antibody, neuroligin-4 X-linked antibody, neuroligin X antibody, neuroligin 4, X-linked antibody

Background: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene. Anti-Neuroligin-4 is ideal for research in Neuroscience, including synaptic transmission and GABAergic inhibition, as well as Cell Adhesion.

Gene Name: Neuroligin 4

Gene ID: 100113365

UniProt: B0F2B4