KCNU1 antibody
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- Target See all KCNU1 Antibodies
- KCNU1 (Potassium Channel, Subfamily U, Member 1 (KCNU1))
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Reactivity
- Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This KCNU1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Western Blotting (WB), Fluorescence Microscopy (FM)
- Purification
- Anti-mSlo3 Antibody was purified by Protein G chromatography. This monoclonal antibody is specific for mouse Slo3 protein. A BLAST analysis was used to suggest cross-reactivity with mSlo3 from mouse based on 100% homology with the immunizing sequence. Cross-reactivity with mSlo3 from other sources has not been determined. Ion Channels research.
- Immunogen
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Immunogen: mSlo3 Antibody was produced in mice by repeated immunizations raised against a fusion protein of mouse Slo3.
Immunogen Type: Recombinant Protein
- Clone
- S2-16
- Isotype
- IgG2b
- Top Product
- Discover our top product KCNU1 Primary Antibody
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- Application Notes
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Immunohistochemistry Dilution: 0.1-1.0 μg/mL
Application Note: Anti-Slo3 Antibody is suitable for use in WB and IF microscopy (mouse sperm). Expect a band approximately ~115 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1-10 μg/mL
IF Microscopy Dilution: 1.0-10 μg/mL
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- Storage
- RT,4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Target
- KCNU1 (Potassium Channel, Subfamily U, Member 1 (KCNU1))
- Alternative Name
- mSlo3 (KCNU1 Products)
- Synonyms
- Kcnma3 antibody, Slo3 antibody, mSlo3 antibody, KCNMC1 antibody, KCa5 antibody, KCa5.1 antibody, potassium channel, subfamily U, member 1 antibody, potassium calcium-activated channel subfamily U member 1 antibody, Kcnu1 antibody, KCNU1 antibody
- Background
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Synonyms: mouse anti-mSlo3 antibody, mouse anti-Slo3 antibody, Potassium channel subfamily U member 1, Calcium-activated potassium channel subunit alpha-3, Calcium-activated potassium channel, subfamily M subunit alpha-3, Slowpoke homolog 3, mSlo3, pH -sensitive maxi potassium channel, Kcnu1, Kcnma3, Slo3
Background: The Slo3 channel is a novel potassium channel abundantly expressed in mammalian speramtocytes- tests have shown that it is expressed in both mouse and human testis. It represents a new and unique type of potassium channel that is regulated by both intracellular pH and membrane voltage. Because of its sensitivity to both pH and voltage, Slo3 may play a role in alkalization-mediated K(+) fluxes associated with sperm capacitation.
Gene Name: Kcnu1
- Gene ID
- 16532
- NCBI Accession
- NP_032458
- UniProt
- O54982
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