BRD2 antibody (Internal Region)

Catalog No. ABIN6657772

Supplier Product No.: 100-401-v88

Product Details anti-BRD2 Antibody

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Binding Specificity: Internal Region

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Supplier Product No.: 100-401-v88

Supplier: Rockland

Purpose: Brd2 Antibody

Cross-Reactivity (Details): Cross reactivity with Brd2 from other species not tested.

Purification: Anti-Brd2 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Sterility: Sterile filtered

Immunogen: Anti-Brd2 Antibody was produced in rabbits by repeated immunizations with a synthetic peptide containing an amino acid sequence from the internal part of mouse Brd2.

Isotype: IgG

Application Details

Application Notes:

ELISA_Dilution: 1:100

Western_Blot_Dilution: 1:1,000

Comment:

Anti-Brd2 Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 68 kDa in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for BRD2

Target: BRD2 (Bromodomain Containing 2 (BRD2))

Alternative Name: Brd2 (BRD2 Products)

Background:

Synonyms: Bromodomain-containing protein 2, Female sterile homeotic-related protein 1, Fsrg-1, Protein RING3

Background: Brd2, a mitogen-activated kinase localized to the nucleus, is a putative transcriptional regulator which interacts with E2F1 and with histone H4 acetylated at 'Lys-13'. It is expressed during development and may be involved in growth control. Brd2 also may play a role in spermatogenesis or folliculogenesis and may be involved in some types of leukemia and in juvenile myoclonic epilepsy. Anti-Brd2 Antibody is ideal for research Gene Expression, Cell Cycle Control and Cancer.

Gene Name: BRD2

Gene ID: 14312

NCBI Accession: NP_001191902

UniProt: Q7JJ13

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection