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Calcineurin alpha antibody

Reactivity: Human, Rat, Cow WB, IHC, ELISA Host: Mouse Monoclonal CC-6 unconjugated
Catalog No. ABIN6657479
  • Target See all Calcineurin alpha products
    Calcineurin alpha
    Reactivity
    Human, Rat, Cow
    Host
    • 4
    Mouse
    Clonality
    • 4
    Monoclonal
    Conjugate
    • 2
    • 1
    • 1
    This Calcineurin alpha antibody is un-conjugated
    Application
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Cow (Bovine), Human, Rat (Rattus)
    Cross-Reactivity (Details)
    Cross reactivity with Calcineurin alpha from other sources has not been determined.
    Purification
    Anti-Calcineurin alpha antibody was purified from mouse ascites by protein A chromatography.  This product reacts with human, rat, and bovine.
    Immunogen

    Immunogen: Calcineurin alpha antibody was produced in mice by repeated immunizations with bovine brain calcineurin.

    Immunogen Type: Other

    Clone
    CC-6
    Isotype
    IgG1
  • Application Notes

    Immunohistochemistry Dilution: 1:100-1:500

    Application Note: Anti-Calcineurin alpha is useful for Immunohistochemistry -P and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~19.3 kDa corresponding to the appropriate cell lysate or extract.

    ELISA Dilution: 1:5000

    Western Blot Dilution: 0.25-0.5 μg/mL

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 1.2 % sodium acetate

    Stabilizer: 2 mg BSA

    0.01 % (w/v) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    RT,4 °C,-20 °C
    Storage Comment
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • Target
    Calcineurin alpha
    Abstract
    Calcineurin alpha Products
    Synonyms
    PPP3CC antibody, protein phosphatase 3 catalytic subunit alpha antibody, PPP3CA antibody
    Background

    Synonyms: CNA2, CNB, CNB1, CALNB1, Protein phosphatase 2B regulatory subunit 1, Protein phosphatase 3 regulatory subunit B alpha isoform 1

    Background: Calcineurin, the Ca(2+)/calmodulin-regulated protein phosphatase, first detected in skeletal muscle and brain, has been found in all cells from yeast to mammals. Calcineurin A alpha (PPP3CA),is located on human chromosomes 4, Chromosomal mapping of the human genes for the calmodulin-dependent protein phosphatase (calcineurin) catalytic subunit. Calcineurin regulates bone formation by the osteoblast. This antibody is suitable for researchers interested in apoptosis, transcription factors, nuclear receptors, cancer research, Immune Response, cardiovascular disease, MAK Kinase Signaling, and AKT Signaling.

    Gene Name: PPP3R1

    Gene ID
    5534
    NCBI Accession
    NP_000936
    UniProt
    P63098
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