STRN4 antibody (Internal Region)

Catalog No. ABIN6657275

Product Details anti-STRN4 Antibody

Target: STRN4 (Striatin, Calmodulin Binding Protein 4 (STRN4))

Binding Specificity: Internal Region

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This STRN4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: Anti-Zinedin Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Zinedin from Mouse, Human, and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Zinedin from other sources has not been determined. Neuroscience research.

Immunogen:

Immunogen: Zinedin Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to an internal region of human Zinedin/Striatin-4.

Immunogen Type: Recombinant Protein

Clone: S88-64

Isotype: IgG2a

Application Details

Application Notes:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-Zinedin Antibody is suitable for use in WB, IHC and IP. Expect a band approximately ~95 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Immunoprecipitation Dilution: User Optimized

Western Blot Dilution: 1 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

0.09 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Target Details for STRN4

Target: STRN4 (Striatin, Calmodulin Binding Protein 4 (STRN4))

Alternative Name: Zinedin (STRN4 Products)

Synonyms: C80611 antibody, ZIN antibody, zinedin antibody, striatin, calmodulin binding protein 4 antibody, striatin 4 antibody, Strn4 antibody, STRN4 antibody

Background:

Synonyms: Striatin-4, Zinedin, ZIN

Background: Zinedin, which encodes a protein of 753aa, shares identical protein-protein interaction domains with striatin and SG2Na. They are all part of the striatin family, are multimodular, WD-repeat and calmodulinbinding proteins. All three proteins bind CaM in the presence of calcium suggesting that they play a role in or depend upon calcium signaling. They are all supposed to also function as scaffolding proteins, linking signaling and eukaryotic endocytosis.

Gene Name: STRN4

Gene ID: 29888

NCBI Accession: NP_037535

UniProt: Q9NRL3