STRN4 antibody (Internal Region)

Catalog No. ABIN6657275

Supplier Product No.: 200-301-g65

Product Details anti-STRN4 Antibody

Target: STRN4 (Striatin, Calmodulin Binding Protein 4 (STRN4))

Binding Specificity: Internal Region

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This STRN4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Supplier Product No.: 200-301-g65

Supplier: Rockland

Purpose: Zinedin Antibody

Cross-Reactivity (Details): A BLAST analysis was used to suggest cross-reactivity with Zinedin from Mouse, Human, and Rat based on 100 % homology with the immunizing sequence.

Purification: Anti-Zinedin Antibody was purified by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: Zinedin Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding to an internal region of human Zinedin/Striatin-4.

Clone: S88-64

Isotype: IgG2a

Application Details

Application Notes:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

IF_Microscopy_Dilution: 1.0-10 μg/mL

Western_Blot_Dilution: 1 μg/mL

Comment:

Anti-Zinedin Antibody is tested for use in WB, IHC and IP. Expect a band approximately ~95kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.09 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for STRN4

Target: STRN4 (Striatin, Calmodulin Binding Protein 4 (STRN4))

Alternative Name: Zinedin (STRN4 Products)

Background:

Synonyms: Striatin-4, Zinedin, ZIN

Background: Zinedin, which encodes a protein of 753aa, shares identical protein-protein interaction domains with striatin and SG2Na. They are all part of the striatin family, are multimodular, WD-repeat and calmodulinbinding proteins. All three proteins bind CaM in the presence of calcium suggesting that they play a role in or depend upon calcium signaling. They are all supposed to also function as scaffolding proteins, linking signaling and eukaryotic endocytosis.

Gene Name: STRN4

Gene ID: 29888

NCBI Accession: NP_037535

UniProt: Q9NRL3