WDR61 antibody

Catalog No. ABIN6655668

Product Details anti-WDR61 Antibody

Target: WDR61 (WD Repeat Domain 61 (WDR61))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR61 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Purpose: SKI8 Antibody

Cross-Reactivity (Details): Cross reactivity with SKI8 from other species was not tested.

Purification: Anti-SKI8 Antibody was purified by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: Anti-SKI8 Antibody was produced in rabbits by repeated immunizations with a recombinant protein of human SKI8.

Isotype: IgG

Application Details

Application Notes:

ChIP_Dilution: 1-5 μg per IP

Western_Blot_Dilution: 1:1,000

Comment:

Anti-SKI8 Antibody is tested for Chromatin Immunoprecipitation and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 33.6 kDa in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for WDR61

Target: WDR61 (WD Repeat Domain 61 (WDR61))

Alternative Name: SKI8 (WDR61 Products)

Synonyms: WDR61 antibody, REC14 antibody, SKI8 antibody, 2700038L12Rik antibody, 2810418I05Rik antibody, RGD1308228 antibody, WD repeat domain 61 antibody, Ski complex subunit Rec14 antibody, WD repeat domain 61 L homeolog antibody, wdr61 antibody, WDR61 antibody, LOC692852 antibody, LOC732907 antibody, rec14 antibody, Wdr61 antibody, wdr61.L antibody

Background:

Synonyms: WD repeat-containing protein 61, Meiotic recombination REC14 protein homolog, SKI8 homolog

Background: SKI8 is a component of the PAF and SKI complex which is composed of SKI2, SKI3 and SKI8. These are involved in transcriptional regulation and events downstream of RNA synthesis. Interaction of the SKI complex with SKI7 links the SKI complex to the exosome in order to perform mRNA degradation. Anti-SKI8 Antibody is ideal for research in Gene Expression.

Gene Name: WDR61

Gene ID: 80349

NCBI Accession: NP_079510

UniProt: Q9GZS3