DUX4 antibody (C-Term)
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- Target See all DUX4 Antibodies
- DUX4 (Double Homeobox 4 (DUX4))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This DUX4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)
- Purification
- Anti-DUX4 Antibody was purified by Protein G chromatography. This monoclonal antibody is specific for human DUX4 protein. A BLAST analysis was used to suggest cross-reactivity with DUX4 from human based on 100% homology with the immunizing sequence. It does not cross react with DUX4c. Cross-reactivity with DUX4 from other sources has not been determined. Transcription Factor research.
- Immunogen
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Immunogen: DUX4 Antibody was produced in mice by repeated immunizations with a recombinant protein corresponding to the C-terminal region of human DUX4 protein.
Immunogen Type: Peptide
- Clone
- P2B1
- Isotype
- IgG1
- Top Product
- Discover our top product DUX4 Primary Antibody
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- Application Notes
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Immunohistochemistry Dilution: User Optimized
Application Note: Anti-DUX4 Antibody is suitable for use in WB, IF, and IHC. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1:1000
IF Microscopy Dilution: User Optimized
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
- Storage
- RT,4 °C,-20 °C
- Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- Target
- DUX4 (Double Homeobox 4 (DUX4))
- Alternative Name
- DUX4 (DUX4 Products)
- Synonyms
- DUX4 antibody, DUX4L antibody, double homeobox, 4 antibody, double homeobox 4 antibody, DUX4 antibody
- Background
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Synonyms: mouse anti-DUX4 Antibody, double homeobox 4, DUX4, Double homeobox protein 4-like protein, DUX4L2, DUX4L3, DUX4L5, DUX4L6, DUX4L7
Background: DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1. Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function. In FSHD individuals, the expression of the full-length DUX4 transcipt is not completely suppressed in skeletal muscle and possibly other differentiated tissues.
Gene Name: DUX2
- Gene ID
- 22947
- NCBI Accession
- NP_149418
- UniProt
- F5GZ66
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