CD8 alpha antibody (FITC)
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- Target See all CD8 alpha (CD8A) Antibodies
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD8 alpha antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS)
- Supplier Product No.
- 200-302-m64
- Supplier
- Rockland
- Purpose
- CD8 Fluorescein Antibody
- Cross-Reactivity (Details)
- Reactivity is observed against human CD8 and chimpanzee.
- Purification
- Fluorescein conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8.
- Sterility
- Sterile filtered
- Immunogen
- Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.
- Clone
- RPA-T8
- Isotype
- IgG1 kappa
- Labeling Ratio
- 2-8
- Top Product
- Discover our top product CD8A Primary Antibody
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- Application Notes
- Optional[Neutralization_Dilution]: 10 μL/10^6 cells (0.25 μg)
- Comment
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Anti-CD8 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 0.1 % Gelatin
Preservative: 0.09 % (w/v) Sodium Azide - Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store vial at 4° C prior to opening. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. DO NOT FREEZE. This product is light sensitive.
- Expiry Date
- 6 months
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- Target
- CD8 alpha (CD8A) (CD8a Molecule (CD8A))
- Alternative Name
- CD8A (CD8A Products)
- Background
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Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL
Background: CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.
Gene Name: CD8
- Gene ID
- 925
- NCBI Accession
- NP_001139345
- UniProt
- P01732
- Pathways
- TCR Signaling
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