Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD8 alpha antibody (FITC)

Rockland 200-302-m64 CD8A Reactivity: Human FACS Host: Mouse Monoclonal RPA-T8 FITC
Rockland
Catalog No. ABIN6655185
Supplier Product No.: 200-302-m64
  • Target See all CD8 alpha (CD8A) Antibodies
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Reactivity
    • 175
    • 104
    • 46
    • 42
    • 13
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 143
    • 123
    • 89
    Mouse
    Clonality
    • 254
    • 96
    • 2
    Monoclonal
    Conjugate
    • 123
    • 41
    • 29
    • 26
    • 24
    • 8
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD8 alpha antibody is conjugated to FITC
    Application
    • 281
    • 113
    • 82
    • 60
    • 58
    • 48
    • 32
    • 20
    • 15
    • 14
    • 13
    • 11
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Supplier Product No.
    200-302-m64
    Supplier
    Rockland
    Purpose
    CD8 Fluorescein Antibody
    Cross-Reactivity (Details)
    Reactivity is observed against human CD8 and chimpanzee.
    Purification
    Fluorescein conjugated CD8 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against human CD8.
    Sterility
    Sterile filtered
    Immunogen
    Anti-CD8 Antibody (Monoclonal) was produced by repeated immunizations with CD8 antigen.
    Clone
    RPA-T8
    Isotype
    IgG1 kappa
    Labeling Ratio
    2-8
    Top Product
    Discover our top product CD8A Primary Antibody
  • Application Notes
    Optional[Neutralization_Dilution]: 10 μL/10^6 cells (0.25 μg)
    Comment

    Anti-CD8 is tested for Flow Cytometry (Cell Surface). Researchers should determine optimal titers for applications that are not stated.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer

    Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: 0.1 % Gelatin

    Preservative: 0.09 % (w/v) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store vial at 4° C prior to opening.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  DO NOT FREEZE. This product is light sensitive.
    Expiry Date
    6 months
  • Target
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Alternative Name
    CD8A (CD8A Products)
    Background

    Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL

    Background: CD8 is a cell surface glycoprotein expressing on thymocytes subsets and cytotoxic T cells and is either a homodimer of two alpha chains, or a heterodimer of one alpha and one beta chain. It acts as a coreceptor during T cell activation through the binding of MHC Class I molecules and is found on T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 associates with LCK with the help of a zinc clasp structure and down-regulates the production of major Th2-type cytokines. CD8 is also known to recruit pUL97 thereby inducing dissolution of the nuclear lamina and facilitating the nuclear export of viral capsids.

    Gene Name: CD8

    Gene ID
    925
    NCBI Accession
    NP_001139345
    UniProt
    P01732
    Pathways
    TCR Signaling
You are here:
Support