Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SPTA1 antibody (AA 356-475)

SPTA1 Reactivity: Human IHC (p) Host: Rabbit Monoclonal SPTA1-2939R unconjugated
Catalog No. ABIN6654212
  • Target See all SPTA1 products
    SPTA1 (Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
    Binding Specificity
    AA 356-475
    Reactivity
    Human
    Host
    • 2
    • 1
    Rabbit
    Clonality
    • 3
    Monoclonal
    Conjugate
    • 3
    This SPTA1 antibody is un-conjugated
    Application
    • 3
    • 2
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Purified
    Purity
    Protein A affinity chromatography
    Immunogen
    A portion of amino acids 356-475 from the human protein was used as the immunogen for the recombinant Spectrin alpha 1 antibody.
    Clone
    SPTA1-2939R
    Isotype
    IgG kappa
  • Application Notes
    Optimal dilution of the recombinant Spectrin alpha 1 antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
    Restrictions
    For Research Use only
  • Buffer
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store the recombinant Spectrin alpha 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Target
    SPTA1 (Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
    Alternative Name
    SPTA1 / Spectrin alpha 1 (SPTA1 Products)
    Background
    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
You are here:
Support