WFDC2 antibody (AA 31-124)

Catalog No. ABIN6654136

Product Details anti-WFDC2 Antibody

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Binding Specificity: AA 31-124

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WFDC2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity purified

Immunogen: Human recombinant protein (amino acids E31-F124) was used as the immunogen for the HE4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HE4 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the HE4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for WFDC2

Target: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Alternative Name: WFDC2 / HE4 (WFDC2 Products)

Synonyms: WFDC3 antibody, WFDC2 antibody, si:ch211-153a8.3 antibody, EDDM4 antibody, HE4 antibody, WAP5 antibody, dJ461P17.6 antibody, 1600023A02Rik antibody, re4 antibody, CE4 antibody, BE-20 antibody, WAP four-disulfide core domain 2 antibody, WFDC2 antibody, wfdc2 antibody, Wfdc2 antibody

Background: WAP four-disulfide core domain protein 2, also known as Human Epididymis Protein 4 (HE4), is a protein that in humans is encoded by the WFDC2 gene. This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

UniProt: Q14508