EIF4E antibody

Catalog No. ABIN659032

Product Details anti-EIF4E Antibody

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This EIF4E antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This EIF4E monoclonal antibody is generated from mouse immunized with EIF4E recombinant protein.

Clone: 163CT48-1-9

Isotype: IgG1 kappa

Application Details

Application Notes: IF: 1:10~50. WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-EIF4E antibody (ABIN659032)

Hoeffer, Santini, Ma, Arnold, Whelan, Wong, Pierre, Pelletier, Klann: "Multiple components of eIF4F are required for protein synthesis-dependent hippocampal long-term potentiation." in: Journal of neurophysiology, Vol. 109, Issue 1, pp. 68-76, (2013) (PubMed).

Target Details for EIF4E

Target: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Alternative Name: EIF4E (EIF4E Products)

Background: EIF4E recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Molecular Weight: 25097

Gene ID: 1977

NCBI Accession: NP_001124150, NP_001124151, NP_001959

UniProt: P06730

Pathways: BCR Signaling