beta Actin antibody

Catalog No. ABIN658990

Product Details anti-beta Actin Antibody

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This beta Actin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), DNA Microscopy (DNA Mic)

Predicted Reactivity: X, B, C, Hs, Pr, Pig, Sh

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This ACTB Monoclonal antibody is generated from mouse immunized with ACTB recombinant protein.

Clone: 137CT26-1-1

Isotype: IgG1, Ig kappa

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:10~50. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-beta Actin antibody (ABIN658990)

Lin, Chen, Huang, Xu: "CYLD Promotes TNF-α-Induced Cell Necrosis Mediated by RIP-1 in Human Lung Cancer Cells." in: Mediators of inflammation, Vol. 2016, pp. 1542786, (2017) (PubMed).

Munoz, Yazdi, Tang, Rivera, Taghipour, Grossman, Boone, Tasciotti: "Localized inhibition of P2X7R at the spinal cord injury site improves neurogenic bladder dysfunction by decreasing urothelial P2X3R expression in rats." in: Life sciences, Vol. 171, pp. 60-67, (2017) (PubMed).

Vispute, Bu, Le, Cheng: "Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via Fgf21 induction." in: Toxicology, Vol. 378, pp. 95-106, (2017) (PubMed).

Bu, Le, Zhang, Zhang, Cheng: "Berberine-induced Inactivation of Signal Transducer and Activator of Transcription 5 Signaling Promotes Male-specific Expression of a Bile Acid Uptake Transporter." in: The Journal of biological chemistry, Vol. 292, Issue 11, pp. 4602-4613, (2017) (PubMed).

Lau, Tang, Casey, Wang: "Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoforms." in: Oncogene, Vol. 36, Issue 27, pp. 3934-3942, (2017) (PubMed).

Martins, Bung, Koch, Richter, Schwarzmüller, Terhardt, Kurtulmus, Niehrs, Rouhi, Lohmann, Pereira, Fröhling, Glimm, Scholl: "Stk33 is required for spermatid differentiation and male fertility in mice." in: Developmental biology, Vol. 433, Issue 1, pp. 84-93, (2017) (PubMed).

Wei, Ma, Ding, Jin, Liu, Chang, Hu, Yu: "Reduced Glutamate Release in Adult BTBR Mouse Model of Autism Spectrum Disorder." in: Neurochemical research, Vol. 41, Issue 11, pp. 3129-3137, (2016) (PubMed).

Harada, Katsuki, Takahashi, Masuda, Yoshinaga, Adachi, Izawa, Kuwamura, Nakano, Yamaji, Inui: "Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic ?-Cells." in: Journal of cellular biochemistry, Vol. 116, Issue 6, pp. 998-1006, (2015) (PubMed).

Koutakis, Miserlis, Myers, Kim, Zhu, Papoutsi, Swanson, Haynatzki, Ha, Carpenter, McComb, Johanning, Casale, Pipinos et al.: "Abnormal accumulation of desmin in gastrocnemius myofibers of patients with peripheral artery disease: associations with altered myofiber morphology and density, mitochondrial dysfunction and ..." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 63, Issue 4, pp. 256-69, (2015) (PubMed).

Vatter, Di, Donaldson, Radu, Maines, Brinton: "Functional analyses of the three simian hemorrhagic fever virus nonstructural protein 1 papain-like proteases." in: Journal of virology, Vol. 88, Issue 16, pp. 9129-40, (2014) (PubMed).

Miyazawa, Tsuji: "Evidence for a novel antioxidant function and isoform-specific regulation of the human p66Shc gene." in: Molecular biology of the cell, Vol. 25, Issue 13, pp. 2116-27, (2014) (PubMed).

Choi, Li, Felsher: "Addiction to multiple oncogenes can be exploited to prevent the emergence of therapeutic resistance." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 32, pp. E3316-24, (2014) (PubMed).

Target Details for beta Actin

Target: beta Actin (ACTB) (Actin, beta (ACTB))

Alternative Name: ACTB (ACTB Products)

Synonyms: BRWS1 antibody, PS1TP5BP1 antibody, ACTA1 antibody, Actx antibody, E430023M04Rik antibody, beta-actin antibody, ps1tp5bp1 antibody, act-2 antibody, actb antibody, B-actin antibody, LOC100174883 antibody, LOC100304816 antibody, A antibody, ACT5C antibody, Ac5C antibody, Act antibody, Act-5C antibody, Act5 antibody, Act5c antibody, Actin antibody, Actin/BAP47 antibody, Actin5C antibody, BAP47 antibody, Bap47 antibody, CG4027 antibody, Dmel\\CG4027 antibody, M32055 antibody, T11 antibody, act antibody, act 5C antibody, act5C antibody, actin antibody, actin5C antibody, anon-EST:fe2D2 antibody, beta-actin/Bap47 antibody, cyt5C antibody, l(1)G0009 antibody, l(1)G0010 antibody, l(1)G0025 antibody, l(1)G0079 antibody, l(1)G0117 antibody, l(1)G0177 antibody, l(1)G0245 antibody, l(1)G0330 antibody, l(1)G0420 antibody, l(1)G0486 antibody, Bact antibody, ACT-5 antibody, ACTB antibody, B-ACTZF antibody, actba antibody, bact antibody, bactin1 antibody, bactzf antibody, wu:fd18f05 antibody, A26C1B antibody, POTE2alpha antibody, POTEACTIN antibody, Beta-actin antibody, actin beta antibody, actin, beta antibody, cytoplasmic actin OlCA1 antibody, beta-actin antibody, Actin 5C antibody, actin gamma 1 antibody, actin, beta 1 antibody, actin, beta L homeolog antibody, beta actin antibody, POTE ankyrin domain family member F antibody, actin, beta like 2 antibody, actin, cytoplasmic 1 antibody, ACTB antibody, Actb antibody, actb antibody, LOC100174883 antibody, LOC100304816 antibody, Act5C antibody, ACTG1 antibody, actb1 antibody, actb.L antibody, LOC100136352 antibody, POTEF antibody, ACTBL2 antibody, LOC109073280 antibody

Background: This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins.

Molecular Weight: 41737

Gene ID: 60

NCBI Accession: NP_001092

UniProt: P60709

Pathways: Myometrial Relaxation and Contraction, Cell-Cell Junction Organization, Maintenance of Protein Location, Phototransduction