NCK2 antibody (N-Term)

Catalog No. ABIN658028

Product Details anti-NCK2 Antibody

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Binding Specificity: AA 63-92, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NCK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human NCK2.

Clone: RB33920

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: NCK2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for NCK2

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Alternative Name: NCK2 (NCK2 Products)

Synonyms: GRB4 antibody, NCKbeta antibody, NCK2 antibody, 4833426I10Rik antibody, Grb4 antibody, Nck-2 antibody, Nck2 antibody, zgc:55283 antibody, fd20h08 antibody, im:7147817 antibody, si:ch211-147g19.3 antibody, wu:fd20h08 antibody, zgc:92024 antibody, NCK adaptor protein 2 antibody, cytoplasmic protein NCK2-like antibody, non-catalytic region of tyrosine kinase adaptor protein 2 antibody, NCK adaptor protein 2a antibody, NCK adaptor protein 2b antibody, NCK2 antibody, Nck2 antibody, LOC100227348 antibody, nck2a antibody, nck2b antibody

Background: This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 42915

Gene ID: 8440

NCBI Accession: NP_001004720, NP_003572

UniProt: O43639

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization