CIDEA antibody (C-Term)

Catalog No. ABIN657978

Product Details anti-CIDEA Antibody

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Binding Specificity: AA 181-209, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIDEA antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CIDEA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the C-terminal region of human CIDEA.

Clone: RB34139

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CIDEA Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for CIDEA

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Alternative Name: CIDEA (CIDEA Products)

Synonyms: CIDE-A antibody, AW212747 antibody, CIDEA antibody, cide-a antibody, MGC89985 antibody, cell death-inducing DFFA-like effector a antibody, cell death-inducing DNA fragmentation factor, alpha subunit-like effector A antibody, cell death-inducing DFFA-like effector a L homeolog antibody, CIDEA antibody, Cidea antibody, cidea antibody, cidea.L antibody

Background: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.

Molecular Weight: 24687

Gene ID: 1149

NCBI Accession: NP_001270

UniProt: O60543