RORB antibody (C-Term)

Catalog No. ABIN657975

Product Details anti-RORB Antibody

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Binding Specificity: AA 329-358, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RORB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-358 amino acids from the C-terminal region of human RORB.

Clone: RB34135

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RORB Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-RORB antibody (ABIN657975)

Mills, Eliseeva, Bersie, Randazzo, Nahreini, Park, Brzezinski: "Combinatorial regulation of a Blimp1 (Prdm1) enhancer in the mouse retina." in: PLoS ONE, Vol. 12, Issue 8, pp. e0176905, (2017) (PubMed).

Target Details for RORB

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Alternative Name: RORB (RORB Products)

Synonyms: RORB antibody, Nr1f2 antibody, LOC100226267 antibody, NR1F2 antibody, ROR-BETA antibody, RZR-BETA antibody, RZRB antibody, bA133M9.1 antibody, nr1f2 antibody, rzrb antibody, sb:eu943 antibody, RZR-beta antibody, Rorbeta antibody, RAR related orphan receptor B antibody, RAR-related orphan receptor B antibody, RAR-related orphan receptor beta antibody, RORB antibody, Rorb antibody, rorb antibody

Background: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation.

Molecular Weight: 53220

Gene ID: 6096

UniProt: Q92753

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway