CLNK antibody (AA 281-308)

Catalog No. ABIN657864

Product Details anti-CLNK Antibody

Target: CLNK (Cytokine-Dependent Hematopoietic Cell Linker (CLNK))

Binding Specificity: AA 281-308

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLNK antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-308 amino acids from the Central region of human MIST.

Clone: RB21953

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MIST Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for CLNK

Target: CLNK (Cytokine-Dependent Hematopoietic Cell Linker (CLNK))

Alternative Name: MIST (CLNK Products)

Synonyms: MIST antibody, Mist antibody, RGD1562417 antibody, cytokine dependent hematopoietic cell linker antibody, cytokine-dependent hematopoietic cell linker antibody, CLNK antibody, Clnk antibody

Background: MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603, BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1, MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326], Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).

Molecular Weight: 49554

Gene ID: 116449

NCBI Accession: NP_443196

UniProt: Q7Z7G1