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Nemo-Like Kinase antibody (C-Term)

NLK Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB34651 unconjugated
Catalog No. ABIN657850
  • Target See all Nemo-Like Kinase (NLK) Antibodies
    Nemo-Like Kinase (NLK)
    Binding Specificity
    • 15
    • 15
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 408-436, C-Term
    Reactivity
    • 70
    • 34
    • 12
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 71
    • 4
    Rabbit
    Clonality
    • 72
    • 3
    Polyclonal
    Conjugate
    • 25
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Nemo-Like Kinase antibody is un-conjugated
    Application
    • 67
    • 31
    • 26
    • 26
    • 19
    • 11
    • 10
    • 10
    • 9
    • 6
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Mouse Nlk antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-436 amino acids from the C-terminal region of mouse Nlk.
    Clone
    RB34651
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NLK Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Mouse Nlk Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    Nemo-Like Kinase (NLK)
    Alternative Name
    Nlk (NLK Products)
    Background
    Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta-catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP. Involved in TGFbeta-mediated mesoderm induction, acting downstream of MAP3K7/TAK1 to phosphorylate STAT3.
    Molecular Weight
    58313
    Gene ID
    100044468, 18099
    NCBI Accession
    NP_032728
    UniProt
    O54949
    Pathways
    Ubiquitin Proteasome Pathway
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