CBX8 antibody (AA 197-230)

Catalog No. ABIN6578183

Product Details anti-CBX8 Antibody

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Binding Specificity: AA 197-230

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CBX8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 197-230 amino acids from the Central region of human CBX8.

Clone: RB51982

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:8000. IHC-P: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for CBX8

Target: CBX8 (Chromobox Homolog 8 (CBX8))

Alternative Name: CBX8 (CBX8 Products)

Synonyms: cbx8 antibody, MGC147589 antibody, Pc3 antibody, PC3 antibody, RC1 antibody, chromobox 8 antibody, chromobox 8 S homeolog antibody, chromobox homolog 8a (Pc class homolog, Drosophila) antibody, cbx8 antibody, CBX8 antibody, Cbx8 antibody, cbx8.S antibody, cbx8a antibody

Background: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Molecular Weight: 43396

UniProt: Q9HC52