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POF1B antibody (AA 337-366)

POF1B Reactivity: Mouse WB Host: Rabbit Polyclonal RB33064 unconjugated
Catalog No. ABIN657749
  • Target See all POF1B Antibodies
    POF1B (Premature Ovarian Failure, 1B (POF1B))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 337-366
    Reactivity
    • 17
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 23
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    This POF1B antibody is un-conjugated
    Application
    • 20
    • 16
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This POF1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-366 amino acids from the Central region of human POF1B.
    Clone
    RB33064
    Isotype
    Ig Fraction
    Top Product
    Discover our top product POF1B Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    POF1B Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    POF1B (Premature Ovarian Failure, 1B (POF1B))
    Alternative Name
    POF1B (POF1B Products)
    Synonyms
    RGD1560798 antibody, 2310066B14Rik antibody, POF antibody, POF2B antibody, POF1B, actin binding protein antibody, premature ovarian failure 1B antibody, Pof1b antibody, POF1B antibody
    Background
    Premature ovarian failure (POF) is characterized by primary or secondary amenorrhea in women less than 40 years old. Two POF susceptibility regions called 'POF1' and 'POF2' have been identified by breakpoint mapping of X-autosome translocations. POF1 extends from Xq21-qter while POF2 extends from Xq13.3 to Xq21.1. This gene, POF1B, resides in the POF2 region. This gene is expressed at trace levels in mouse prenatal ovary and is barely detectable or absent from adult ovary, in human and in the mouse respectively. This gene's expression is restricted to epithelia with its highest expression in the epidermis, and oro-pharyngeal and gastro-intestinal tracts. The protein encoded by this gene binds non-muscle actin filaments. The role this gene may play in the etiology of premature ovarian failure remains to be determined.
    Molecular Weight
    68065
    Gene ID
    79983
    NCBI Accession
    NP_079197
    UniProt
    Q8WVV4
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