MARCH11 antibody (C-Term)

Catalog No. ABIN657732

Product Details anti-MARCH11 Antibody

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Binding Specificity: AA 308-337, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCH11 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MARCH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human MARCH11.

Clone: RB31539

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MARCH11 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for MARCH11

Target: MARCH11 (Membrane-Associated Ring Finger (C3HC4) 11 (MARCH11))

Alternative Name: MARCH11 (MARCH11 Products)

Synonyms: MARCH-XI antibody, 9630025C22 antibody, RGD1559945 antibody, membrane associated ring-CH-type finger 11 antibody, membrane-associated ring finger (C3HC4) 11 antibody, MARCH11 antibody, March11 antibody

Background: MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN)-multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]).

Molecular Weight: 43878

Gene ID: 441061

NCBI Accession: NP_001096032

UniProt: A6NNE9