RANGAP1 antibody (N-Term)

Catalog No. ABIN657698

Product Details anti-RANGAP1 Antibody

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Binding Specificity: AA 20-49, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANGAP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RANGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human RANGAP1.

Clone: RB33892

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RANGAP1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for RANGAP1

Target: RANGAP1 (Ran GTPase Activating Protein 1 (RANGAP1))

Alternative Name: RANGAP1 (RANGAP1 Products)

Synonyms: Fug1 antibody, RANGAP antibody, SD antibody, ATRANGAP1 antibody, RAN GTPASE-ACTIVATING PROTEIN 1 antibody, RAN GTPase activating protein 1 antibody, RanGAP1 antibody, fug1 antibody, rangap1b antibody, rna1p antibody, C79654 antibody, mKIAA1835 antibody, rangap1 antibody, rangap1a antibody, Protein rna1 antibody, CG9999 antibody, CT28175 antibody, Dmel\CG9999 antibody, RGP1_DROME antibody, Ran antibody, RanGAP antibody, RanGap antibody, RanGap1 antibody, Scl antibody, Sd antibody, Sd-RanGAP antibody, Sd-RanGap antibody, dRanGAP antibody, ranGAP antibody, ranGap antibody, rangap antibody, zgc:154097 antibody, Ran GTPase activating protein 1 antibody, RAN GTPase activating protein 1 antibody, ran GTPase activating protein 1 antibody, Ran GTPase activating protein 1 S homeolog antibody, Ran GTPase activating protein 1 L homeolog antibody, Ran GAP Rna1 antibody, Ran GTPase activating protein antibody, RAN GTPase activating protein 1a antibody, RANGAP1 antibody, TERG_02084 antibody, rangap1.S antibody, Rangap1 antibody, rangap1.L antibody, rna1 antibody, RanGAP antibody, rangap1a antibody

Background: RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88 % identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

Molecular Weight: 63542

Gene ID: 5905

NCBI Accession: NP_001265580, NP_002874

UniProt: P46060

Pathways: M Phase, Protein targeting to Nucleus