TRIM23 antibody (N-Term)

Catalog No. ABIN657564

Product Details anti-TRIM23 Antibody

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Binding Specificity: AA 147-175, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM23 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRIM23 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human TRIM23.

Clone: RB33243

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TRIM23 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for TRIM23

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Alternative Name: TRIM23 (TRIM23 Products)

Synonyms: zgc:153463 antibody, ARD1 antibody, ARFD1 antibody, RNF46 antibody, 6330516O20Rik antibody, AI450195 antibody, Arfd1 antibody, Ard1 antibody, tripartite motif containing 23 antibody, tripartite motif containing 23 S homeolog antibody, tripartite motif-containing 23 antibody, trim23 antibody, trim23.S antibody, TRIM23 antibody, Trim23 antibody

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.

Molecular Weight: 64067

Gene ID: 373

NCBI Accession: NP_001647, NP_150230, NP_150231

UniProt: P36406