ZFX antibody (AA 288-317)

Catalog No. ABIN657487

Product Details anti-ZFX Antibody

Target: ZFX (Zinc Finger Protein, X-Linked (ZFX))

Binding Specificity: AA 288-317

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFX antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZFX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 288-317 amino acids from the Central region of human ZFX.

Clone: RB32448

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ZFX Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for ZFX

Target: ZFX (Zinc Finger Protein, X-Linked (ZFX))

Alternative Name: ZFX (ZFX Products)

Synonyms: Zfx5 antibody, Zfx5,6 antibody, Zfx6 antibody, RGD1562664 antibody, xzfy-1 antibody, zfy1 antibody, ZNF926 antibody, zinc finger protein X-linked antibody, zinc finger protein, X-linked S homeolog antibody, zinc finger protein, X-linked antibody, Zfx antibody, zfx.S antibody, ZFX antibody

Background: This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.

Molecular Weight: 90522

Gene ID: 7543

NCBI Accession: NP_001171555, NP_001171556, NP_001171557, NP_003401

UniProt: P17010