MCOLN1 antibody (C-Term)

Catalog No. ABIN657474

Product Details anti-MCOLN1 Antibody

Target: MCOLN1 (Mucolipin 1 (MCOLN1))

Binding Specificity: AA 531-560, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCOLN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Pr, M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MCOLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-560 amino acids from the C-terminal region of human MCOLN1.

Clone: RB33839

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MCOLN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for MCOLN1

Target: MCOLN1 (Mucolipin 1 (MCOLN1))

Alternative Name: MCOLN1 (MCOLN1 Products)

Background: This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca(2+), Fe(2+), Na(+), K(+), and H(+), and is modulated by changes in Ca(2+) concentration. Mutations in this gene result in mucolipidosis type IV.

Molecular Weight: 65022

Gene ID: 57192

NCBI Accession: NP_065394

UniProt: Q9GZU1

Pathways: Transition Metal Ion Homeostasis