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CrkL antibody (N-Term)
CRKL
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB33678
unconjugated
Product Details anti-CrkL Antibody
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Target
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CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Binding Specificity
All epitopes for CrkL antibodies
AA 50-79, N-Term
Reactivity
All reactivities for CrkL antibodies
Human
Host
All hosts for CrkL antibodies
Rabbit
Clonality
All clonalities for CrkL antibodies
Polyclonal
Conjugate
All conjugates for CrkL antibodies
This CrkL antibody is un-conjugated
Application
All applications for CrkL antibodies
Western Blotting (WB)
Predicted Reactivity
M, Rat
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CRKL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human CRKL.
Clone
RB33678
Isotype
Ig Fraction
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Discover our top product CRKL Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000. WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
CRKL Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date
6 months
Target Details for CrkL
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Target
CrkL (CRKL)
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Alternative Name
CRKL (CRKL Products )
Synonyms
CRKL antibody, wu:fa55g05 antibody, wu:fj60e01 antibody, zgc:63469 antibody, 1110025F07Rik antibody, AA589403 antibody, AI325100 antibody, Crkol antibody, CRK like proto-oncogene, adaptor protein antibody, v-crk avian sarcoma virus CT10 oncogene homolog-like antibody, CRKL antibody, crkl antibody, Crkl antibody
Background
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Molecular Weight
33777
Gene ID
1399
NCBI Accession
NP_005198
UniProt
P46109
Pathways
Interferon-gamma Pathway , Neurotrophin Signaling Pathway , Signaling of Hepatocyte Growth Factor Receptor
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