This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This TBCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human TBCC.
CFC antibody, 2810055C19Rik antibody, tubulin folding cofactor C antibody, tubulin-specific chaperone C antibody, TBCC antibody, Tbcc antibody
Background
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex, interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.