BCCIP antibody
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- Target See all BCCIP Antibodies
- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This BCCIP antibody is un-conjugated
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Application
- Immunohistochemistry (IHC)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human BCCIP (NP_510868.1).
- Isotype
- IgG
- Top Product
- Discover our top product BCCIP Primary Antibody
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- Application Notes
- IHC 1:100-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- BCCIP (BRCA2 and CDKN1A Interacting Protein (BCCIP))
- Alternative Name
- BCCIP (BCCIP Products)
- Synonyms
- zgc:110272 antibody, mp:zf637-1-000774 antibody, BCCIP antibody, DKFZp459K2416 antibody, MGC82792 antibody, tok-1 antibody, MGC89311 antibody, TOK-1 antibody, TOK1 antibody, 1110013J05Rik antibody, BRCA2 and CDKN1A interacting protein antibody, BRCA2 and CDKN1A interacting protein L homeolog antibody, BCCIP antibody, bccip antibody, bccip.L antibody, Bccip antibody
- Background
- This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
- Molecular Weight
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Observed_MW: 50kDa
Calculated_MW: 33kDa/35kDa/36kDa
- Gene ID
- 56647
- UniProt
- Q9P287
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