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TMEM43 antibody

TMEM43 Reactivity: Human, Mouse IHC, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6571807
  • Target See all TMEM43 Antibodies
    TMEM43 (Transmembrane Protein 43 (TMEM43))
    Reactivity
    Human, Mouse
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    This TMEM43 antibody is un-conjugated
    Application
    • 18
    • 16
    • 15
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human TMEM43 (NP_077310.1).
    Isotype
    IgG
    Top Product
    Discover our top product TMEM43 Primary Antibody
  • Application Notes
    WB 1:500-1:2000 IHC 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    TMEM43 (Transmembrane Protein 43 (TMEM43))
    Alternative Name
    TMEM43 (TMEM43 Products)
    Synonyms
    zgc:85946 antibody, ARVC5 antibody, ARVD5 antibody, EDMD7 antibody, LUMA antibody, 1200015A22Rik antibody, transmembrane protein 43 antibody, TMEM43 antibody, tmem43 antibody, Tmem43 antibody
    Background
    This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
    Molecular Weight

    Observed_MW: 45kDa

    Calculated_MW: 44kDa

    Gene ID
    79188
    UniProt
    Q9BTV4
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