ERCC4 antibody

Catalog No. ABIN6571574

Product Details anti-ERCC4 Antibody

Target: ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERCC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purification: Affinity purification

Immunogen: Recombinant protein of human ERCC4

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IP 1:20 - 1:50

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ERCC4

Target: ERCC4 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 4 (ERCC4))

Alternative Name: ERCC4 (ERCC4 Products)

Synonyms: ERCC11 antibody, FANCQ antibody, RAD1 antibody, XPF antibody, AI606920 antibody, Xpf antibody, RGD1560340 antibody, fi03a05 antibody, zgc:63468 antibody, wu:fi03a05 antibody, ercc11 antibody, rad1 antibody, xpf antibody, ERCC4 antibody, LOC100231158 antibody, ERCC excision repair 4, endonuclease catalytic subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 4 antibody, excision repair cross-complementation group 4 antibody, excision repair cross-complementation group 4 L homeolog antibody, ERCC4 antibody, Ercc4 antibody, ercc4 antibody, ercc4.L antibody, XPF antibody

Background:

Synonyms: DNA excision repair protein ERCC 4,DNA excision repair protein ERCC-4,DNA excision repair protein ERCC4,DNA repair endonuclease XPF,DNA repair protein complementing XP F cells,DNA repair protein complementing XP-F cells,ERCC 11,ERCC 4,ERCC11,ERCC4,Excision repair complementing defective in Chinese hamster,Excision repair cross complementing rodent repair deficiency complementation group 4,excision repair cross-complementation group 4,FANCQ,RAD 1,RAD1,Xeroderma pigmentosum complementation group F,Xeroderma pigmentosum group F complementing protein,Xeroderma pigmentosum group F-complementing protein,Xeroderma pigmentosum VI,XP,group G,XP6,XPF

Background: The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).

Molecular Weight:

Observed_MW: 120kDa

Calculated_MW: 42kDa/104kDa

Gene ID: 2072

UniProt: Q92889

Pathways: DNA Damage Repair