PCDHb5 antibody (AA 278-307)

Catalog No. ABIN657154

Product Details anti-PCDHb5 Antibody

Target: PCDHb5 (Protocadherin beta 5 (PCDHb5))

Binding Specificity: AA 278-307

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHb5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-307 amino acids from the Central region of human PCDHB5.

Clone: RB33054

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for PCDHb5

Target: PCDHb5 (Protocadherin beta 5 (PCDHb5))

Alternative Name: PCDHB5 (PCDHb5 Products)

Synonyms: PCDH-BETA5 antibody, Pcdhb4A antibody, PcdhbE antibody, protocadherin beta 5 antibody, protocadherin beta-5 antibody, PCDHB5 antibody, Pcdhb5 antibody, LOC786489 antibody

Background: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

NCBI Accession: NP_056484

UniProt: Q9Y5E4