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NDST1 antibody (C-Term)

NDST1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB33030 unconjugated
Catalog No. ABIN657148
  • Target See all NDST1 Antibodies
    NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))
    Binding Specificity
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 820-849, C-Term
    Reactivity
    • 39
    • 1
    • 1
    Human
    Host
    • 36
    • 3
    Rabbit
    Clonality
    • 37
    • 2
    Polyclonal
    Conjugate
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NDST1 antibody is un-conjugated
    Application
    • 35
    • 20
    • 16
    • 13
    • 5
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M, Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This NDST1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 820-849 amino acids from the C-terminal region of human NDST1.
    Clone
    RB33030
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NDST1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Target
    NDST1 (N-Deacetylase/N-Sulfotransferase (Heparan Glucosaminyl) 1 (NDST1))
    Alternative Name
    NDST1 (NDST1 Products)
    Synonyms
    HSST antibody, NST1 antibody, 1200015G06Rik antibody, Hsst antibody, NDST-1 antibody, fj47c03 antibody, ndst1 antibody, wu:fj47c03 antibody, NDST1 antibody, N-deacetylase and N-sulfotransferase 1 antibody, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 antibody, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1b antibody, N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 S homeolog antibody, NDST1 antibody, Ndst1 antibody, ndst1b antibody, ndst1 antibody, ndst1.S antibody
    Background
    NDST1 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate that can ultimately serve as L-selectin ligands, thereby playing a role in inflammatory response.
    Molecular Weight
    100868
    NCBI Accession
    NP_001534
    UniProt
    P52848
    Pathways
    Regulation of Systemic Arterial Blood Pressure by Hormones, Glycosaminoglycan Metabolic Process
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