LECT1 antibody
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- Target See all LECT1 Antibodies
- LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LECT1 antibody is un-conjugated
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Application
- Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein of human LECT1 (NP_008946.1).
- Isotype
- IgG
- Top Product
- Discover our top product LECT1 Primary Antibody
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- Application Notes
- IF 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- LECT1 (Leukocyte Cell Derived Chemotaxin 1 (LECT1))
- Alternative Name
- LECT1 (LECT1 Products)
- Synonyms
- chm1 antibody, chm-i antibody, bricd3 antibody, MGC53801 antibody, MGC82444 antibody, chondromodulin-I antibody, Lect1 antibody, BRICD3 antibody, CHM-I antibody, CHM1 antibody, MYETS1 antibody, Bricd3 antibody, ChM-I antibody, Chm-1 antibody, chondromodulin L homeolog antibody, leukocyte cell derived chemotaxin 1 antibody, chondromodulin antibody, cnmd.L antibody, lect1 antibody, CNMD antibody, cnmd antibody, Cnmd antibody
- Background
- This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
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Observed_MW: 37kDa
Calculated_MW: 36kDa/37kDa
- Gene ID
- 11061
- UniProt
- O75829
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