ORC5 antibody (AA 227-256)

Catalog No. ABIN657025

Product Details anti-ORC5 Antibody

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Binding Specificity: AA 227-256

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC5 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ORC5L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the Central region of human ORC5L.

Clone: RB31078

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for ORC5

Target: ORC5 (Origin Recognition Complex, Subunit 5 (ORC5))

Alternative Name: ORC5L (ORC5 Products)

Background: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].

Molecular Weight: 50283

NCBI Accession: NP_002544, NP_859531

UniProt: O43913

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA