CKMT1A antibody
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- Target See all CKMT1A Antibodies
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CKMT1A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human CKMT1A
- Isotype
- IgG
- Top Product
- Discover our top product CKMT1A Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CKMT1A (Creatine Kinase, Mitochondrial 1A (CKMT1A))
- Alternative Name
- CKMT1A (CKMT1A Products)
- Synonyms
- CKMT1 antibody, Mt-CK antibody, ScCKmit antibody, UbCKmit antibody, mi-CK antibody, Ckmt1 antibody, CKMT1B antibody, Mia-CK antibody, U-MtCK antibody, creatine kinase, mitochondrial 1A antibody, creatine kinase U-type, mitochondrial-like antibody, creatine kinase, mitochondrial 1, ubiquitous antibody, creatine kinase U-type, mitochondrial antibody, CKMT1A antibody, LOC100228000 antibody, Ckmt1 antibody, LOC100725326 antibody
- Background
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Synonyms: Acidic-type mitochondrial creatine kinase,CKMT,CKMT1,CKMT1B,Creatine kinase mitochondrial 1 (ubiquitous),Creatine kinase mitochondrial 1B,Creatine kinase U type mitochondrial,Creatine kinase U-type,KCRU,Mia-CK,mitochondrial,U-MtCK,Ubiquitous mitochondrial creatine kinase,UMTCK
Background: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase, this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80 % homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
- Molecular Weight
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Observed_MW: 47kDa
Calculated_MW: 47kDa/50kDa
- Gene ID
- 1159
- UniProt
- P12532
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