CD8B antibody
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- Target See all CD8B Antibodies
- CD8B (CD8b Molecule (CD8B))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CD8B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human CD8B
- Isotype
- IgG
- Top Product
- Discover our top product CD8B Primary Antibody
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- Application Notes
- WB 1:200 - 1:500
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CD8B (CD8b Molecule (CD8B))
- Alternative Name
- CD8B (CD8B Products)
- Synonyms
- Cd8b antibody, Ly-3 antibody, Ly-C antibody, Lyt-3 antibody, CD8B1 antibody, LEU2 antibody, LY3 antibody, LYT3 antibody, P37 antibody, Cd8b1 antibody, CD8b molecule antibody, CD8 antigen, beta chain 1 antibody, Cd8b antibody, CD8B antibody, Cd8b1 antibody
- Background
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Synonyms: CD8b antigen,CD8 antigen beta polypeptide 1 (p37),CD8 antigen beta polypeptide 1,CD8 beta,CD8b,CD8b molecule,CD8B,CD8B1,Leu2,Ly3,LYT3,MGC119115,P37,T cell surface glycoprotein CD8 beta chain,T lymphocyte surface glycoprotein beta chain,T-cell surface glycoprotein CD8 beta chain
Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
- Molecular Weight
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Observed_MW: 45kDa
Calculated_MW: 20kDa/22kDa/23kDa/24kDa/25kDa/27kDa
- Gene ID
- 926
- UniProt
- P10966
- Pathways
- TCR Signaling
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