HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (AA 79-107), (N-Term) antibody

Catalog No. ABIN656942

Product Details

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Binding Specificity: AA 79-107, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HERV-FRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the N-terminal region of human HERV-FRD.

Clone: RB32774

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: HERV-FRD Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References

Cui, Wang, Lu, Wang, Zheng, Li, Yang, Jia, Zhao, Wang, Wang, Wang, Zhu, Lin, Wang: "Effects of individually silenced N-glycosylation sites and non-synonymous single-nucleotide polymorphisms on the fusogenic function of human syncytin-2." in: Cell adhesion & migration, Vol. 10, Issue 1-2, pp. 39-55, (2017) (PubMed).

Chang, Wang, Cui, Peng, Fan, Xue, Yang: "PLAC1 is involved in human trophoblast syncytialization." in: Reproductive biology, Vol. 16, Issue 3, pp. 218-224, (2017) (PubMed).

Li, Zheng, Wang, Lu, Zhu, Lin, Wang, Yu, Fu: "Involvement of nephrin in human placental trophoblast syncytialization." in: Reproduction (Cambridge, England), Vol. 149, Issue 4, pp. 339-46, (2015) (PubMed).

Target Details

Target: HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)

Alternative Name: HERV-FRD (Herv-frd Products)

Synonyms: ERVFRDE1 antibody, GLLL6191 antibody, HERV-FRD antibody, HERV-W/FRD antibody, UNQ6191 antibody, envFRD antibody, Gm52 antibody, Syna antibody, endogenous retrovirus group FRD member 1, envelope antibody, ERVFRD-1 antibody, Ervfrd-1 antibody

Target Type: Viral Protein

Background: Human endogenous retroviruses (HERVs) make up approximately 8 % of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1, MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).

Molecular Weight: 59523

Gene ID: 405754

NCBI Accession: NP_997465

UniProt: P60508