PHD1 antibody
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- Target See all PHD1 (EGLN2) Antibodies
- PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PHD1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Purification
- Affinity purification
- Immunogen
- A synthetic peptide of human EGLN2
- Isotype
- IgG
- Top Product
- Discover our top product EGLN2 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000 IP 1:20 - 1:50
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
- Alternative Name
- EGLN2 (EGLN2 Products)
- Background
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Synonyms: DKFZp434E026,EGL nine (C.elegans) homolog 2,Egl nine homolog 2 (C. elegans),Egl nine homolog 2,EGLN 2,EGLN2,EGLN2,EIT 6,EIT6,Estrogen-induced tag 6,HIF P4H 1,HIF PH1,HIF prolyl hydroxylase 1,HIF-PH1,HIF-prolyl hydroxylase 1,HIFPH 1,HIFPH1,HPH 3,HPH-1,HPH-3,HPH3,Hypoxia inducible factor prolyl hydroxylase 1,Hypoxia-inducible factor prolyl hydroxylase 1,P4H1,PHD 1,PhD1,prolyl hydroxylase domain containing protein 1,Prolyl hydroxylase domain-containing protein 1
Background: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.
- Molecular Weight
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Observed_MW: 55kDa
Calculated_MW: 40kDa/43kDa
- Gene ID
- 112398
- UniProt
- Q96KS0
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis
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