Heparanase 2 antibody (C-Term)
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- Target See all Heparanase 2 (HPSE2) Antibodies
- Heparanase 2 (HPSE2)
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Binding Specificity
- AA 451-480, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Heparanase 2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- M
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This HPSE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-480 amino acids from the C-terminal region of human HPSE2.
- Clone
- RB32587
- Isotype
- Ig Fraction
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- Application Notes
- WB: 1:1000. IHC-P: 1:10~50
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- HPSE2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Expiry Date
- 6 months
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- Target
- Heparanase 2 (HPSE2)
- Alternative Name
- HPSE2 (HPSE2 Products)
- Synonyms
- si:dkeyp-22h2.2 antibody, HPA2 antibody, HPR2 antibody, UFS antibody, UFS1 antibody, Gm968 antibody, Hpa2 antibody, heparanase 2 (inactive) antibody, inactive heparanase-2 antibody, heparanase 2 antibody, HPSE2 antibody, LOC100070602 antibody, hpse2 antibody, Hpse2 antibody
- Background
- Endoglycosidase which is a cell surface and extracellular matrix-degrading enzyme. Cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Also implicated in the extravasation of leukocytes and tumor cell lines. Due to its contribution to metastasis and angiogenesis, it is considered to be a potential target for anti-cancer therapies.
- Molecular Weight
- 66596
- Gene ID
- 60495
- NCBI Accession
- NP_001159716, NP_001159717, NP_001159718, NP_068600
- UniProt
- Q8WWQ2
- Pathways
- Glycosaminoglycan Metabolic Process
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