HIST2H2BE antibody

Catalog No. ABIN6569006

Product Details anti-HIST2H2BE Antibody

Target: HIST2H2BE (Histone H2B Type 2-E (HIST2H2BE))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST2H2BE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human HIST2H2BE

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HIST2H2BE

Target: HIST2H2BE (Histone H2B Type 2-E (HIST2H2BE))

Alternative Name: HIST2H2BE (HIST2H2BE Products)

Background:

Synonyms: GL105,H2B,H2B histone family member Q,H2B-GL105,H2B.1,H2B/q,H2B2E,H2BFQ,H2BGL105,H2BQ,HIST2H2BE,Histone 2 H2be,histone cluster 2, H2be,histone H2B GL105,histone H2B type 2 E,Histone H2B type 2-E,histone H2B type 2E,Histone H2B-GL105,Histone H2B.q,histone H2BGL105

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.

Molecular Weight:

Observed_MW: 15kDa

Calculated_MW: 13kDa

Gene ID: 8349

UniProt: Q16778