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LRWD1 antibody

LRWD1 Reactivity: Mouse, Human, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6568759
  • Target See all LRWD1 Antibodies
    LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
    Reactivity
    • 16
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Human, Rat
    Host
    • 21
    Rabbit
    Clonality
    • 21
    Polyclonal
    Conjugate
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    This LRWD1 antibody is un-conjugated
    Application
    • 20
    • 13
    • 12
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human Lrwd1
    Isotype
    IgG
    Top Product
    Discover our top product LRWD1 Primary Antibody
  • Application Notes
    WB 1:200 - 1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
    Alternative Name
    Lrwd1 (LRWD1 Products)
    Synonyms
    CENP-33 antibody, ORCA antibody, 1200011O22Rik antibody, AU042569 antibody, AW548074 antibody, Orca antibody, si:dkey-261j4.9 antibody, wu:fb78b03 antibody, wu:ft31b04 antibody, leucine rich repeats and WD repeat domain containing 1 antibody, leucine-rich repeats and WD repeat domain containing 1 antibody, microRNA 5090 antibody, leucine-rich repeats and WD repeat domain containing 1 L homeolog antibody, LRWD1 antibody, Lrwd1 antibody, lrwd1 antibody, MIR5090 antibody, lrwd1.L antibody
    Background

    Synonyms: 1200011O22Rik,AU042569,AW548074,DKFZp434K1815,Leucine rich repeats and WD repeat domain containing 1,Leucine-rich repeat and WD repeat-containing protein 1,LRWD1,LRWD1,ORC-associated protein,ORCA,Origin recognition complex-associated protein

    Background: The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

    Molecular Weight

    Observed_MW: 65kDa

    Calculated_MW: 70kDa

    Gene ID
    222229
    UniProt
    Q9UFC0
    Pathways
    Chromatin Binding
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