MRPL50 antibody (C-Term)

Catalog No. ABIN656854

Product Details anti-MRPL50 Antibody

Target: MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))

Binding Specificity: AA 119-147, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL50 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RM50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-147 amino acids from the C-terminal region of human RM50.

Clone: RB27656

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RM50 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for MRPL50

Target: MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))

Alternative Name: RM50 (MRPL50 Products)

Synonyms: ANON-65Eb antibody, BcDNA:GM06185 antibody, BcDNA:RE06140 antibody, CG8612 antibody, Dmel\\CG8612 antibody, MRP-L50 antibody, anon-65Eb antibody, DKFZp468B0910 antibody, AA408971 antibody, AI317351 antibody, D4Wsu125e antibody, mitochondrial ribosomal protein L50 antibody, mitochondrial 54S ribosomal protein MRPL50 antibody, mRpL50 antibody, Mrpl50 antibody, MRPL50 antibody

Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.

Molecular Weight: 18325

Gene ID: 54534

NCBI Accession: NP_061924

UniProt: Q8N5N7