Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
M
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GPR34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the Central region of human GPR34.
GPR34
Reactivity: Human, Rat, Mouse
FACS
Host: Rabbit
Polyclonal
FITC
Application Notes
WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
GPR34 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date
6 months
Hasegawa, Patel, Ettehadieh, Li, Lim: "Topogenesis and cell surface trafficking of GPR34 are facilitated by positive-inside rule that effects through a tri-basic motif in the first intracellular loop." in: Biochimica et biophysica acta, Vol. 1863, Issue 7 Pt A, pp. 1534-51, (2016) (PubMed).
G protein-coupled receptors (GPCRs), such as GPR34, are integral membrane proteins containing 7 putative transmembrane domains (TMs). These proteins mediate signals to the interior of the cell via activation of heterotrimeric G proteins that in turn activate various effector proteins, ultimately resulting in a physiologic response.