POLE2 antibody
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- Target See all POLE2 Antibodies
- POLE2 (Polymerase (DNA Directed), epsilon 2 (p59 Subunit) (POLE2))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This POLE2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human POLE2
- Isotype
- IgG
- Top Product
- Discover our top product POLE2 Primary Antibody
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- Application Notes
- WB 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- POLE2 (Polymerase (DNA Directed), epsilon 2 (p59 Subunit) (POLE2))
- Alternative Name
- DNA pol epsilon B (POLE2 Products)
- Synonyms
- DPE2 antibody, polymerase (DNA directed), epsilon 2, accessory subunit L homeolog antibody, DNA polymerase epsilon 2, accessory subunit antibody, polymerase (DNA directed), epsilon 2, accessory subunit antibody, polymerase (DNA directed), epsilon 2 (p59 subunit) antibody, pole2.L antibody, POLE2 antibody, pole2 antibody, Pole2 antibody
- Background
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Synonyms: DNA polymerase epsilon subunit 2,DNA polymerase epsilon subunit B,DNA polymerase II subunit 2,DPE 2,DPE2,DPOE2,POLE 2,POLE2,Polymerase (DNA directed) epsilon 2 (p59 subunit),Polymerase (DNA directed) epsilon 2,polymerase (DNA directed),epsilon 2,accessory subunit,Polymerase,DNA,epsilon-2
Background: DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency.
- Molecular Weight
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Observed_MW: 59kDa
Calculated_MW: 56kDa/59kDa
- Gene ID
- 5427
- UniProt
- P56282
- Pathways
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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