LOXL3 antibody (C-Term)

Catalog No. ABIN656764

This Rabbit Polyclonal antibody specifically detects LOXL3 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for LOXL3 antibody (C-Term) (ABIN656764)

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOXL3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32569

Product Details anti-LOXL3 Antibody

Binding Specificity: AA 715-744, C-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LOXL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 715-744 amino acids from the C-terminal region of human LOXL3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: LOXL3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for LOXL3

Target: LOXL3 (Lysyl Oxidase-Like 3 (LOXL3))

Alternative Name: LOXL3

Background: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined.

Molecular Weight: 83166

Gene ID: 84695

NCBI Accession: NP_115992

UniProt: P58215