DFNB31 antibody

Catalog No. ABIN6567020

Product Details anti-DFNB31 Antibody

Target: DFNB31 (Deafness, Autosomal Recessive 31 (DFNB31))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DFNB31 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human WHRN

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DFNB31

Target: DFNB31 (Deafness, Autosomal Recessive 31 (DFNB31))

Alternative Name: WHRN (DFNB31 Products)

Synonyms: DFNB31 antibody, CIP98 antibody, PDZD7B antibody, USH2D antibody, WHRN antibody, WI antibody, Cip98 antibody, Whrn antibody, 1110035G07Rik antibody, AW122018 antibody, AW742671 antibody, C430046P22Rik antibody, Dfnb31 antibody, wi antibody, whirlin antibody, WHRN antibody, LOC100555508 antibody, Whrn antibody

Background:

Synonyms: Whirlin,Autosomal Recessive Deafness Type 31 Protein,DFNB31,Deafness Autosomal Recessive 31,CASK-Interacting Protein CIP98,KIAA1526,PDZD7B,CIP98,USH2D,WI,WHRN,KIAA1526

Background: This gene is thought to function in the organization and stabilization of sterocilia elongation and actin cystoskeletal assembly, based on studies of the related mouse gene. Mutations in this gene have been associated with autosomal recessive non-syndromic deafness and Usher Syndrome. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 110kDa

Calculated_MW: 37kDa/55kDa/59kDa/96kDa

Gene ID: 25861

UniProt: Q9P202

Pathways: Sensory Perception of Sound