WDR11 antibody

Catalog No. ABIN6566998

Product Details anti-WDR11 Antibody

Target: WDR11 (WD Repeat Domain 11 (WDR11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WDR11 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human WDR11

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for WDR11

Target: WDR11 (WD Repeat Domain 11 (WDR11))

Alternative Name: WDR11 (WDR11 Products)

Synonyms: Brwd2 antibody, WDR11 antibody, PHIP antibody, BRWD2 antibody, DR11 antibody, HH14 antibody, WDR15 antibody, 2900055P10Rik antibody, AW489876 antibody, mKIAA1351 antibody, WD repeat domain 11 antibody, Wdr11 antibody, WDR11 antibody

Background:

Synonyms: Bromodomain and WD repeat containing protein 2,Bromodomain and WD repeat domain containing 2,Bromodomain- and WD repeat-containing protein 2, formerly,BRWD2,BRWD2, formerly,DKFZp434L1715,DR11,FLJ42531,HH14,KIAA1351,WD repeat containing protein 11,WD repeat containing protein 15,WD repeat domain 11,WD repeat domain 15,WDR 11,WDR15

Background: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10,19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.

Molecular Weight:

Observed_MW: 130kDa

Calculated_MW: 136kDa

Gene ID: 55717

UniProt: Q9BZH6