POLR1C antibody

Catalog No. ABIN6566549

Product Details anti-POLR1C Antibody

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: Affinity purification

Immunogen: Recombinant Protein of human POLR1C

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for POLR1C

Target: POLR1C (Polymerase (RNA) I Polypeptide C, 30kDa (POLR1C))

Alternative Name: POLR1C (POLR1C Products)

Background:

Synonyms: 40  kDa,AA409007,AA959927,Ac2-127,AC40,AL024089,DNA directed RNA polymerase I subunit C,DNA directed RNA polymerases I and III 40 kDa polypeptide,DNA directed RNA polymerases I and III subunit RPAC1,DNA-directed RNA polymerase I subunit C,DNA-directed RNA polymerases I and III 40 kDa polypeptide,DNA-directed RNA polymerases I and III subunit RPAC1,MGC105583,MGC161175,POLR1C,POLR1E,Polymerase (RNA) I polypeptide C,30  kDa,RNA polymerase 1 1,RNA polymerase I subunit C,RNA polymerases I and III subunit AC1,RP3-337H4.4,RPA39,RPA40,RPA5,RPAC1,RPAC1,RPC40,Rpo1 1,TCS3

Background: The protein encoded by this gene is a subunit of both RNA polymerase I and RNA polymerase III complexes. The encoded protein is part of the Pol core element. Mutations in this gene have been associated with Treacher Collins syndrome (TCS) and hypomyelinating leukodystrophy 11. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 39kDa

Calculated_MW: 38kDa/39kDa

Gene ID: 9533

UniProt: O15160