Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Predicted Reactivity
B, Pr, M
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This GPD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 606-634 amino acids from the C-terminal region of human GPD2.
GPD2
Reactivity: Human, Rat, Horse, Rabbit, Dog, Guinea Pig, Cow, Hamster, Monkey, Bat, Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
GPD2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date
6 months
Sánchez, Balagué, Matilla-Dueñas: "Ataxin-1 regulates the cerebellar bioenergetics proteome through the GSK3β-mTOR pathway which is altered in Spinocerebellar ataxia type 1 (SCA1)." in: Human molecular genetics, Vol. 25, Issue 18, pp. 4021-4040, (2017) (PubMed).
The protein encoded by this gene localizes to the inner mitochondrial membrane and catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate, using FAD as a cofactor. Along with GDP1, the encoded protein constitutes the glycerol phosphate shuttle, which reoxidizes NADH formed during glycolysis. Two transcript variants encoding the same protein have been found for this gene.