NXN antibody (AA 221-249)

Catalog No. ABIN656415

Product Details anti-NXN Antibody

Target: NXN (Nucleoredoxin (NXN))

Binding Specificity: AA 221-249

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NXN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the Central region of human NXN.

Clone: RB27657

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: NXN Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-NXN antibody (ABIN656415)

Jia, Cui, Meng, Xing, Shen, Wang, Liu, Wang, Lian, Zhang: "Malignant transformation of human gastric epithelium cells via reactive oxygen species production and Wnt/β-catenin pathway activation following 40-week exposure to ochratoxin A." in: Cancer letters, Vol. 372, Issue 1, pp. 36-47, (2016) (PubMed).

Target Details for NXN

Target: NXN (Nucleoredoxin (NXN))

Alternative Name: NXN (NXN Products)

Synonyms: l11Jus13 antibody, NRX antibody, TRG-4 antibody, ns:zf-es94 antibody, zgc:110449 antibody, nucleoredoxin antibody, nucleoredoxin S homeolog antibody, Nxn antibody, NXN antibody, nxn.S antibody, nxn antibody

Background: NXN functions as a redox-dependent negative regulator of the Wnt signaling pathway. May function as a transcriptional regulator. May regulate phosphatase 2A (By similarity).

Molecular Weight: 48392

Gene ID: 64359

NCBI Accession: NP_001192248, NP_071908

UniProt: Q6DKJ4