SPG7 antibody (AA 115-141)

Catalog No. ABIN656408

Product Details anti-SPG7 Antibody

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Binding Specificity: AA 115-141

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPG7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SPG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-141 amino acids from the Central region of human SPG7.

Clone: RB23654

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SPG7 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for SPG7

Target: SPG7 (Spastic Paraplegia 7 (SPG7))

Alternative Name: SPG7 (SPG7 Products)

Synonyms: CAR antibody, CMAR antibody, PGN antibody, SPG5C antibody, AI452278 antibody, AU015315 antibody, Cmar antibody, SPG7, paraplegin matrix AAA peptidase subunit antibody, SPG7 antibody, Spg7 antibody

Background: This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq].

Molecular Weight: 88235

Gene ID: 6687

NCBI Accession: NP_003110, NP_955399

UniProt: Q9UQ90